Myers Cocktail vs NAD+ IV: Which Should You Book?
A Myers' Cocktail is a 30 to 45 minute vitamin and mineral IV that helps you feel better this week. A NAD+ IV is a 2 to 4 hour cellular energy infusion that works more slowly and costs more. If you are weighing a Myers cocktail vs NAD+ for the first time, start with the Myers' Cocktail. Move to NAD+ only if brain fog, not general fatigue, is the main problem you want to solve.
That is the short answer. The longer answer matters because these two IVs sit next to each other on every drip menu in Arizona, and they are not interchangeable. One replaces nutrients, and the other is a coenzyme your mitochondria use to make energy. They feel different during the drip, cost different amounts, and suit different weeks of your life.
Myers cocktail vs NAD+ at a glance
| Factor | Myers' Cocktail | NAD+ IV |
|---|---|---|
| What it is | Vitamin and mineral blend in 1 liter of saline | Nicotinamide adenine dinucleotide, a coenzyme, in 1 liter of saline with B-complex |
| Main job | Replace nutrients, rehydrate, take the edge off fatigue and stress | Support cellular energy production and mental clarity |
| Session time | 30 to 45 minutes | 2 to 4 hours |
| How it feels during the drip | Mild warmth, sometimes a magnesium flush | Warmth, chest pressure, or stomach flutter if the drip runs too fast |
| When most people notice a difference | Same day to 24 hours | Same day to 48 hours, often building over a short series |
| Best for | A run-down week, low-grade fatigue, immune support, a monthly reset | Persistent brain fog, slow recovery, longevity-focused protocols |
| RevivaGo price | $199 (Mega Myers' Cocktail $249) | $279 and up, based on dose |
| Bottom line | Start here. Fastest, most affordable, easiest to fit into a weekday | Step up here when brain fog is the main complaint and you can block an afternoon |
Both are delivered to your home by a licensed RN, NP, or paramedic under physician oversight. Neither is a stimulant. Neither replaces sleep, food, or a conversation with your doctor about fatigue that will not lift.
What a Myers' Cocktail actually is
A Myers' Cocktail is a classic intravenous blend of magnesium, calcium, B-complex vitamins, and vitamin C. It is named after Dr. John Myers, a Baltimore physician who used the formula in the 1960s and 1970s. Dr. Alan Gaby described it in detail in a 2002 review in Alternative Medicine Review, and the ingredient list has barely changed since.
At RevivaGo, the Myers' Cocktail IV comes in 1 liter of normal saline, so you get hydration along with the nutrients. Most patients book it when they feel depleted but not sick: the school-year grind, back-to-back travel, a stretch of short nights, or the week after a cold. Many tell us they notice a lift in energy and mood the same day. Our guide to Myers' Cocktail benefits, ingredients, and cost has the full breakdown.
The evidence is real but modest, and we say so. The best-known trial, a 2009 randomized study in the Journal of Alternative and Complementary Medicine, gave weekly Myers' Cocktail infusions to people with fibromyalgia. Both the IV group and the placebo group improved, and the gap between them was not statistically significant at eight weeks.
What is not in dispute is the delivery advantage. A 2004 study in the Annals of Internal Medicine found that intravenous vitamin C produces blood concentrations many times higher than the same dose taken by mouth, because IV delivery skips the limits of intestinal absorption.
What a NAD+ IV actually is
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell. Your mitochondria use it to turn food into ATP, the energy your cells spend on repair, focus, and recovery. Levels fall with age. A 2012 study in PLoS ONE measured NAD+ in human skin tissue and found substantially lower levels in adults over 45, a finding often summarized as roughly a 50 percent drop between ages 30 and 60.
A NAD+ IV delivers the coenzyme straight into the bloodstream, and it has to run slowly. A 2019 study in Frontiers in Aging Neuroscience infused 750 mg of NAD+ over six hours in healthy adults. Blood NAD+ did not rise until about the two hour mark, which the authors read as rapid uptake into tissue, and no serious adverse effects were reported. That slow uptake is why a NAD+ session takes 2 to 4 hours, and why running it faster tends to cause warmth, chest tightness, or nausea.
People book NAD+ for a different reason than they book a Myers' Cocktail. The typical patient is not wiped out from one bad week. They describe months of feeling mentally dull, slow to recover from workouts or travel, or a specific interest in longevity protocols. Our article on NAD+ therapy for brain fog and low energy covers who tends to respond and what the research supports.
Myers cocktail vs NAD+ for energy and afternoon crashes
This is the question we hear most in September. Coffee stops working by 2 p.m., and someone wants to know which IV fixes it.
For most people, the Myers' Cocktail is the better first answer. An afternoon crash after a run of short sleep, skipped meals, and Arizona heat is usually a hydration and nutrient problem. B vitamins are cofactors for energy metabolism, magnesium is one of the most common shortfalls in the American diet, and vitamin C supports immune function during back-to-school germ season. A Myers' Cocktail covers all of that in under an hour.
NAD+ is the better answer when the crash has been there for months, sleep is already decent, and the main complaint is fog rather than fatigue. Rereading the same email three times, feeling flat rather than tired. That pattern points toward cellular energy support, which is the job NAD+ is built for. It is also what we recommend when someone has already tried a Myers' Cocktail, got hydration relief, and saw no change in mental clarity.
Not sure which pattern fits? That is itself an answer. Start with the Myers' Cocktail. It costs less, takes 45 minutes, and tells you quickly whether the problem was replenishment.
Cost and time: what each one asks of you
Price and schedule decide this for a lot of East Valley patients, so here are the real numbers. RevivaGo shows every price before you book, with no travel fee inside our service area.
- Myers' Cocktail: $199, or $249 for the higher-dose Mega Myers' Cocktail. Plan on 30 to 45 minutes plus a few minutes of intake. It fits a lunch hour or the gap between school pickup and dinner.
- NAD+ IV: starts at $279 and rises with dose. Plan on 2 to 4 hours. Most patients book a Saturday morning or a work-from-home afternoon and sit on their own couch while it runs.
- NAD+ shot: $35 at RevivaGo pop-up events. A quick intramuscular option if you want to try NAD+ before committing to a full infusion. See NAD injections in Queen Creek for how the shot compares to the IV.
Phoenix-area drip bars typically list NAD+ infusions from $250 to $600 or more, and most expect you to drive there and sit in a shared lounge for the full session. A four hour NAD+ drip is much easier to tolerate in your own living room. The full service menu and pricing is posted for anyone to check.
Our pick: start with Myers, add NAD+ if brain fog is the main job
Here is the decision framework we use with patients who ask us to just tell them what to book.
- Name the main complaint in one word. If the word is tired, drained, or dehydrated, book a Myers' Cocktail. If the word is foggy, slow, or flat, keep reading.
- Check the timeline. A bad two weeks is a Myers' Cocktail week. A bad three months, with sleep and diet already reasonable, is when NAD+ earns its price and its afternoon.
- Check the calendar. If you cannot block 2 to 4 hours this week, the choice is made for you. Book the Myers' Cocktail now and schedule NAD+ for a weekend.
- Reassess after the first session. If the Myers' Cocktail cleared the fatigue but the fog stayed, that is a clean signal to step up to NAD+. If it cleared both, you have found your monthly reset.
This is why we tell people to start with the Myers' Cocktail this month. It is the treatment most likely to help the most people, at the lowest cost, in the least time. NAD+ is a real tool with a narrower job.
Combining Myers' Cocktail and NAD+ in one plan
You can get both, and some longevity-focused patients do. The common approach is a NAD+ infusion every few weeks with a Myers' Cocktail in between, so nutrient replacement stays current while the NAD+ series builds. Your provider will not run them as one bag, because NAD+ needs its own slow drip rate.
If you want a combined plan, mention it at booking. Our medical team reviews every intake before treatment and will tell you whether the cadence makes sense for your history. Our overview of NAD+ IV therapy benefits and what the science says is worth reading before that conversation.
Safety, side effects, and who should skip each
Both treatments are delivered by Arizona-licensed RNs, NPs, and paramedics using sterile single-use supplies, with physician oversight on every visit. That is our standard whether the bag holds a Myers' Cocktail or NAD+, and it is the standard you should expect from any IV provider in the East Valley.
The Myers' Cocktail is usually uneventful. Magnesium can cause a brief warm flush, and a fast push can lower blood pressure for a moment, which is why we run it at a controlled rate. Patients with significant kidney disease or certain heart rhythm conditions need physician clearance first.
NAD+ has a more noticeable sensation profile. Warmth, chest pressure, stomach fluttering, and mild nausea are common if the drip runs fast, and they usually settle once your provider slows it down. NAD+ is not appropriate during pregnancy or breastfeeding, and patients on certain medications should talk with the medical team first.
Neither IV replaces evaluation for persistent fatigue. Thyroid disease, anemia, and sleep apnea are common causes that no infusion will fix. This article is educational and is not medical advice.
Myers cocktail vs NAD+ FAQ
Is NAD+ better than a Myers' Cocktail?
No, NAD+ is not better in general. It is better for one specific problem: persistent brain fog and slow recovery tied to cellular energy. For general fatigue, dehydration, stress, and immune support, the Myers' Cocktail works faster, costs less, and takes 45 minutes instead of several hours. Most first-time patients should start with the Myers' Cocktail and step up to NAD+ only if the fog remains.
Can you get a Myers' Cocktail and NAD+ at the same time?
Yes, both can be part of one wellness plan, but they are given as separate infusions, not one bag. NAD+ requires a slow, dedicated drip. A typical combined plan alternates a NAD+ session every few weeks with a Myers' Cocktail in between. Tell us at booking and our medical team will confirm the cadence fits your health history.
How long does a NAD+ IV take compared to a Myers' Cocktail?
A Myers' Cocktail takes 30 to 45 minutes. A NAD+ IV takes 2 to 4 hours, depending on dose and how comfortably you tolerate the drip. Research on NAD+ infusion shows blood levels do not rise until roughly two hours in, which is why the infusion cannot be rushed. Mobile delivery makes the longer session far easier, since you spend it at home.
How much does a Myers' Cocktail cost vs NAD+ in Arizona?
At RevivaGo, a Myers' Cocktail is $199 and a Mega Myers' Cocktail is $249. NAD+ IV therapy starts at $279 and increases with dose. Phoenix-area clinics list NAD+ anywhere from $250 to $600 or more per session. There is no travel fee inside our East Valley service area, the price shown at booking is the price you pay, and both treatments are HSA and FSA eligible.
Do I need a prescription for a Myers' Cocktail or NAD+ IV?
No prescription is required for either treatment. You complete a short medical intake when you book, and our physician-led medical team reviews it before your provider arrives. If anything in your history makes one treatment a poor fit, we will tell you before you are charged. Details on the intake process are on our FAQ page.
Ready to reset?
If you have been going back and forth on Myers cocktail vs NAD+, pick the Myers' Cocktail this month. It is the faster, more affordable reset, and it will tell you within a day whether nutrients and hydration were the missing piece. If the fog outlasts the fatigue, NAD+ is waiting, and you will know it is the right next step instead of guessing.
A licensed provider can be at your door in Queen Creek, Gilbert, San Tan Valley, or Mesa, often the same day. Book your Myers' Cocktail or NAD+ IV, settle the Myers cocktail vs NAD+ question for yourself, and get on with your week.
RevivaGo proudly serves Queen Creek, Gilbert, San Tan Valley, and the greater East Valley area. All treatments are administered by licensed healthcare professionals under physician oversight.